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Vial filling machines and processing solutions

One of the major challenges for IMA Life is to implement the latest technologies in aseptic vial filling, whilst ensuring compliance with the highest cGMP’s standards in filling accuracy.

From the decontamination of containers, through depyrogenation, up to liquid vial filling or powder vial filling, closing and capping operations, all our efforts are targeted to avoid any possible contamination risk while delivering the highest performance.

The very compact and versatile design of IMA Life injectable vial filling machines, allows for suitable integration under isolator or different containment solutions without changing the basic machine configuration and minimising human intervention in the processing area.

The external washers complete the range of vial filling line and fit the market’s increasing demand for decontamination solutions to remove product particles from the outside of vials.

Our expertise

1. Washing and Depyrogenating

The decontamination technology is a crucial path in drug processing lines, that is why container washing before and after the filling phase is so important.

Over 50 years of experience in the production of equipment for vial washing combined with constant commitment to innovation, make IMA Life a world leader in the field. The equipment range comes complete with the external vial washers which respond to the increasing demand of filled and capped vial decontamination.

The depyrogenating tunnels installed after the vial washing machines are designed to satisfy any production requirement and are suitable for any kind of application: they come both in the standard and in the dry heat sterilisation version, and can be easily integrated into lines designed to handle high-toxic compounds and/or in lines with isolators.


2. Aseptic Filling and Stoppering

IMA Life machines for aseptic filling are distinguished by their rigorous detail design and are the result of careful research in fluid dynamics, to guarantee maximum product protection of all aseptic filling environments (such as traditional clean rooms, isolation technology or other containment solutions).

Compact and ergonomic design ensures great flexibility for all types of layout. Statistical and 100% IPC control of filled weight along with very advanced CIP/SIP units allow the machines to reach a very high standard in product quality. Aseptic processing of vials is certainly one of the most critical activities in primary drug packaging. 


3. Capping

The primary purpose of vial capping is to secure the closure in place, ensuring the integrity of the pharmaceutical product. Capping also serves to provide a tamper-evident seal, assuring end-users that the product has not been opened or compromised. This process can be performed under controlled and sterile conditions, either downstream or by direct integration in the machine frame as a module.

IMA Life vial capping machines feature a broad range of application capabilities: from traditional aluminium caps, with or without flip-off, to the most sophisticated caps such as add-vantage, bio-set and monovial closures.


4. Labelling

The IMA Life production range includes a vast array of vial labelling machines, which can be supplied in stand-alone version or as an integral part of complete packaging lines.

The Sensitive and Sensitive Roto series of vial labellers can apply any kind of self-adhesive labels (wrap-around, front, rear or both sides) and, thanks to the configuration flexibility of the operative groups, can fit overprinting devices and camera vision systems to read and check data.

These machines feature different solutions to align the packaging of pharmaceutical products to emerging requirements in terms of Track & Trace of the final products.


Want to know more?

Our Machines Portfolio

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VEGA
VEGA

Containers coming in contact with parenteral preparations must be rendered sterile and non-pyrogenic, process resulting particularly successful with the VEGA Series, where the easy configurable washing sequence enhances the efficiency of the cleaning procedure

Small Volume Injectable’s star
HYDRA
HYDRA

HYDRA was created after many years of research and development focusing on container decontamination for injectable drugs. Designed according to the cGMP guidelines, the machine features the highest quality standards required by the pharmaceutical industry.

The imperative for effective washing.
HYDRA 100/300/400
HYDRA 100/300/400

Conceived for outer surface decontamination of pharmaceutical containers after the filling process, Hydra 100/300/400 minimizes the legal risk of long-term exposure for packaging operators and medical personnel handling cytotoxic products or potent compounds.

A step forward in decontamination technology
BLUE GALAXY
BLUE GALAXY

All pharmacopoeia indicate Escherichia Coli type 5 as the endotoxin to be used for checking that a de-pyrogenation process is accomplished correctly. A de-pyrogenation process has to initially guarantee at least a log 3 reduction of endotoxins.

High technology for the safety of sterilization process
ALU
ALU

The longstanding experience in the development and production of capping machines for vials has been channelled into ALU. Unique in style and built to deliver top-level performance, this machine will drive your productivity to a higher degree of efficiency.

Caps the best, caps the rest!
STERICAP
STERICAP

Conceived to provide high capping precision, STERICAP ensures the most remarkable performance. Compact and with a simple and essential design, it is a competitive solution in terms of speed, flexibility and ease of use.

Capping essentials
XTREMA
XTREMA

The main concern of the pharmaceutical packaging market has always been the integrity of the drug, and, in the case of parenteral dosage forms, its sterility. XTREMA indeed embodies the latest technological breakthrough in aseptic filling.

eXperience the eXtreme
XTREMA PWD
XTREMA PWD

The continued emergence of multi-drug resistance bacteria is a global issue.
The development of new antibiotics, especially those with new modes of action, is imperative to help treat new infections. This is the scenario where XTREMA PWD has been designed.

Cutting-edge powder microdosing
SMART 300 PWD AUGER
SMART 300 PWD AUGER

The rising demand for operator safety in aseptic processing, when handling high-potent powdered substances, has boosted the research and the adoption of innovative aseptic dosing technologies replacing the traditional methods.

Performance enhanced through innovation.
SMART
SMART

Time and ease of use are of the essence with small to medium batch production, but with SMART, IMA expertise has gone even further, combining proven technology with high quality standards and the reliability required for all aseptic filling needs.

Inspired by excellence
SMART PWD
SMART PWD

Today certain bacteria have developed resistance to antibiotics that were once commonly used to treat them. The implementation of more powerful antibiotics, and new aseptic technologie, like SMART PWD contribute to solving this serious public health issue.

Breaking new ground in powder processing
SMART DB2
SMART DB2

Sterile bags have many applications in the pharma market and IMA LIFE can provide high-speed turnkey solutions starting from the automatic loading and decontamination of the sterile empty bags up to their final collection.

Multipurpose bag-filling made smart.
EASYFILL PWD
EASYFILL PWD

Delivering powder dosing excellence with ease, EASYFILL PWD boasts our consolidated technology within easy reach of pharma companies, with a guarantee that only IMA Life can give as an undisputed leader in powder microdosing.

Delivering powder dosing excellence.
SENSITIVE AV
SENSITIVE AV

However well an ampoule is labelled, the clinical outcome of any injection depends on the correct drug being administered and the only certain way of achieving this is for the label to be appropriately applied and clearly red.

Graduate with honours in labelling
SENSITIVE ROTO
SENSITIVE ROTO

Where great performance and high-speed labelling of vials and bottles are required, Sensitive Roto comes into play. Versatile and reliable, it ensures an extremely precise application of labels providing information related to the content of the containers.

Perfection is all-around.

Complete line solutions

IMA Life’s aseptic and pharmaceutical products are intended for applications requiring equipment of high scientific and technological content, where the industry must comply with very strict standards.
IMA Life’s product range includes washing equipment, depyrogenating tunnels, liquid filling and closing in aseptic environments of vials, ampoules and “Ready-To-Use” components, microdosing and macrodosing filling of aseptic powders, isolation systems and containment solutions as well as industrial, pilot and laboratory freeze-dryers, which can be combined with the industry’s widest range of automated loading and unloading systems. Lyophilisation process developments, continuous aseptic spray freeze-drying technology complete the array of machines on offer. IMA Life also offers filling and closing machines of non-aseptic pharmaceuticals and cosmetics, syringe assembly and labelling machines, labellers for vials, ampoules, BFS (Blow Fill Seal), shaped containers and cartons, blowing machines, depackers, tray loaders and other ancillary equipment. For innovative solutions with the highest technical standards.

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