One of the major challenges for IMA Life is to implement the latest technologies in aseptic filling, whilst ensuring compliance with the highest cGMP’s standards in filling accuracy.

From the decontamination of containers, through depyrogenation, up to filling, closing and capping operations, all our efforts are targeted to avoid any possible contamination risk while delivering the highest performance.

The very compact and versatile design of IMA Life machines for filling liquids and powders into ampoules and vials, allows for suitable integration under isolator or different containment solutions without changing the basic machine configuration and minimising human intervention in the processing area.

The external washers complete the range and fit the market’s increasing demand for decontamination solutions to remove product particles from the outside of ampoules and vials.

For more than half a century, IMA Life has provided the benchmark for freeze drying solutions to the pharmaceutical and biotech industries. The machine range includes industrial FD,  solutions for pilot work or clinical trial production or even R&D laboratory freeze dryers. These last freeze dryers are available for the USA and Canadian markets only.

This wide range of custom-built freeze dryers are available as stand-alone units or integrated in complete lines including automatic loading and unloading systems for vial transfer.

IMA Life’s steady investments in R&D initiatives have resulted in innovative solutions in the lyophilisation process and technologies such as:

• Veriseq ^TM, advanced innovative controlled nucleation technology capable of producing sterile cryogenic ice fog (Ice Fog Nucleation)
• Fusion^TM shelves produced in-house using an automated manufacturing process to ensure lower operating costs, enhanced process control and reduced risk.
• Fusion Plus^TM, further improvement of the Fusion technology to avoid sticking stoppers. This proven solution consists of a low-adhesion coating applied to the lower shelf surface and it is patented worldwide.
• KryoAir,  new 100% green refrigerant, using air as the refrigerant used in freeze dryers. The system is based on a series of compression/cooling/expansion steps of AIR, which can be cooled to a temperature as low as -100° C.
• Sentinel-LYO, IMA Life’s cloud-based system for freeze-drying data analytics and health monitoring.
• WiSe, multi-point, battery-free wireless temperature sensors, developed for monitoring product temperature.
• Quantum mass spectrometry, a multipurpose device performing quantitative, real-time, process-relevant measurements.
• Lynfinity technology which brings to the market a robust yet gentle continuous aseptic process for spray freeze drying.
• Lynfinity LAB, designed for lab environments, Lynfinity LAB features the same freezing process present on the production Lynfinity, generating uniform frozen droplets from liquid formulation.

The IMA Life production range includes a vast array of linear and rotary labelling machines for vials, ampoules, bottles, blow-fill-seal containers and cartons.

Supplied in stand-alone versions or as an integral part of complete packaging lines, they can apply any kind of self-adhesive labels (wrap-around, front, rear or both sides) on standard or irregularly shaped plastic or glass containers, as well as vignette and tamper-evident sealing on both aeroplane style and reverse tuck cartons.

These machines feature different solutions to align the packaging of pharmaceutical products to emerging requirements in terms of Track & Trace of the final products.

Thanks to the configuration flexibility of the operative groups, the labelling machines can fit overprinting devices and camera vision systems to read and check data.

The full service offering encompasses a multitude of specially developed packages to boost production efficiency, anticipate maintenance requirements or implement rapid corrective measures. A vast selection of training modules for key operational aspects also covers process yield and quality control as well as giving technological insight into the machinery. To complete the services provided, IMA Life also supports customers with equipment upgrades, total overhaul and line relocation.

Located in Tonawanda (USA), at the IMA Life North America facility, the Lab4Life Laboratory consists of a certified clean room, analytical support laboratory, product formulation, filling and full-size freeze drying equipment necessary for the development of pharmaceutical and biopharmaceutical products in batch sizes up to 20 litres. The laboratory includes a highly skilled team of professionals who provide assistance to our customers worldwide.