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IMA Life solutions for the lyophilisation process

IMA Life provides a wide range of solutions for lyophilisation, from processes to freeze-dryers.

LYNFINITY is just a drop away.

The current technology focuses on bringing to the market a robust yet gentle continuous aseptic process for spray-freeze-drying with an eye toward achieving high throughput and high cycle efficiency.

LYNFINITY

Raising productivity and reducing downtime is now possible in a continuous aseptic process, with constant monitoring from fermentation to final packaging.
IMA Life LYNFINITY spray-freeze-drying has been conceived to minimise risks and increase controls compared to the traditional FD process.
The only continuous aseptic spray-freeze-drying process.


The coolest laboratory spray freezing module.
LYnfinity starts here.

Discover it for yourself at:

Interpack – Düsseldorf, GERMANY, Feb. 25 – March 3, 2021
Interphex – New York, USA, April 20-22, 2021

LYNFINITY LAB

Enabling simple access to exclusive continuous aseptic spray freeze-drying technologies developed by IMA Life, LYNFINITY LAB is a high-tech, stand-alone module. Featuring an identical freezing process to the one implemented on LYnfinity at production scale, the laboratory version facilitates model building and cycle development. Scientists and lab technicians can easily test a formulation and collect vital data before switching to a production scenario.

LYNFINITY LAB, the coolest laboratory spray freezing module, where continuous aseptic spray freeze-drying starts.

VERISEQ® NUCLEATION

An advanced innovative controlled nucleation technology capable of producing sterile cryogenic ice fog and circulating it with a lyophiliser chamber to ensure reliable and prompt top-down nucleation of the vial-contained pharmaceutical formulations at an optimal temperature.

CUMULUS™ LF

An innovative cryogenic cooling technology using liquid nitrogen (LIN) as a cooling agent to overcome the performance and environmental limitations of mechanical systems.

PASCALAIR

A 100% green refrigeration system using air as the refrigeration fluid. The system is based on a series of compression/cooling/expansion steps of air, which can be cooled to a temperature as low as -100 °C.

 

WISE

A system composed of wireless battery-free sensors integrated in the vial stopper, capable of making three measurements with a spatial resolution of less than 1 mm. Such multi-point sensing capabilities allow temperature gradient measuring within the product across the entire batch.

QUANTUM

A smart miniature mass spectrometer, a non-invasive technique capable of performing quantitative real-time process-relevant measurements. A multipurpose device designed for use in pharma freeze-dryers, it detects contaminants and process gases at concentrations down to ppm levels.

FUSION TM– FUSION PLUS TM

IMA Life’s patented FusionTM shelves are built in-house by a fully automated manufacturing process, ensuring higher quality and increased process reliability. They are designed and finished to improve the lyophilisation outcome and to reduce operating costs and energy consumption. The Fusion TM shelves are lighter and more resistant than conventional solutions and offer enhanced heat transfer properties.

 

LYOMAX

The machine offers the most comprehensive range of custom-built freeze-dryers for those who require more than a standard solution. Lyomax can provide the answer from 1 m2 to 100 m2 applying state-of-the-art engineering in vacuum, refrigeration, stoppering and heat-transfer technology.

LYOFAST

A range of freeze dryers providing support for all lyophilisation requirements. Lyofast offers superior quality, reduced lead times, cost-effectiveness and simplifies the validation process. The machine features freeze-drying areas from 4 m2 to 50 m2.

MINIMAX

MINIMAX is a GMP small-scale freeze dryer developed to address the demands involved in handling small production batches. Similarly to the LYOMAX industrial freeze dryer, MINIMAX benefits from all-round performance, a high level of redundancy and various configurable options making it a reliable and versatile solution for each application. MINIMAX can be integrated with isolation technology and automatic vial-loading systems. The unit is pre-arranged to support the processing of non-aqueous solvents and high potent products. Available in six configurations with shelf areas from 1.0 up to 3.9 m2, MINIMAX ensures an ice condenser capacity ranging from 29 to 78 kg with minimum condenser temperatures of – 75°C.

LYOFAST MINI

Designed for laboratory developments, pilot and industrial production, Lyofast Mini features a very compact design. It is available in four different configurations with shelf areas from 1.1 to 2.8 m2 and ice condenser capacity ranging from 28 to 58 kg with minimum condenser temperatures of -75°C.

MINIFAST

It is the connection between bench-top and industrial freeze-dryers and the ideal solution for product development and process cycle optimisation. Minifast is available in two models with shelf areas of 0.4 and 1.1 m2 and the ice condenser capacity ranging from 8 to 20 kg with minimum condenser temperatures of -85°C.