SMART DB2: Sterile Bag Filling and Closing Machine • IMA Group

SMART DB2

Sterile Bag Filling and Closing Machine

Sterile bags have many applications in the pharma market and IMA LIFE can provide high-speed turnkey solutions starting from the automatic loading and decontamination of the sterile empty bags up to their final collection.

Multipurpose bag-filling made smart.

Working with flexible materials used in sterile bags does not contribute to making an aseptic filling process perfectly repeatable. Along the DB2 processing line, groups feature special technical solutions to overcome the non-repeatability issue, and Smart DB2 accomplishes the liquid and powder filling operations of the multi-chamber, Ready-To-Use sterile bags. The first filling process is made with powder drugs by means of dosing disks. The second filling process is made with liquid products, by means of mass-flow technology.

The integrated CIP SIP system allows cleaning and sterilisation-in-place procedures of both liquid and powder products, according to authority’s guidelines, minimising the need to remove and autoclave parts, and granting the SAL (Sterilisation Assurance Level).

Production Plant

IMA Life

SMART DB2 Highlights

1.
Suitable for high batch production with output up to 42 bags per minute with a filling volume of 50ml for the liquid section and 3.5 grams for the powder section. Bag size to be defined in accordance with customer requirements at an early stage of the project.

2.
Minimum human intervention is required: major activities/issues are solved through robot interactions. 

3.
Automatic 100% liquid and powder tare and gross check-weighing of the bags.

4.
Whole line contained under isolation technology to avoid any contamination risk and maintain the sterility class.

5.
Both powder filling and liquid filling systems are cleaned and sterilised by integrated CIP SIP (Cleaning In Place - Sterilisation In Place) technology.

Automated devices, robotic technologies and physical barriers are implemented to minimise operator intervention and maintain aseptic conditions.

Technical Data
Machine Layout

SMART DB2 Gallery

Rail positioning

Cap removal for powder dosing

Empty bag pick up

Liquid filling and vacuum forming

Recapping after liquid filling

Liquid filling internal view

Powder dosing unit

Powder dosing and vacuum forming

Gross scaling

Recapping after powder dosing

Powder dosing internal view

Rail extraction from the carrier

Robotic bag transportation