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QUANTUM
Smart miniature mass spectrometer
Leakage into a freeze dryer may originate from various sources. The leak rate should be monitored periodically to maintain the integrity of the system and, should the rate exceed specified limits, to determine the actual leak site for repair purposes.
Leakage into a freeze dryer may originate from various sources. The leak rate should be monitored periodically to maintain the integrity of the system and, should the rate exceed specified limits, to determine the actual leak site for repair purposes.
Detect, quantify, control.
QUANTUM smart Mass Spectrometer is a non-invasive technique capable of performing real-time, process-relevant, quantitative measurements. A multipurpose device for use in pharmaceutical freeze dryers, it detects contaminants and process gases at concentrations down to ppm levels. Not only does this allow for silicone oil detection and for non-aqueous solvent detection, but QUANTUM can also be used as a system leak detection tool and as a process analytical tool for scale-up and development studies.
Robust, reliable and ultra-compact, QUANTUM houses a pre-calibrated modular sensor comprising a long-lasting ion source, a quadrupole array mass filter, electron multiplier, and the Faraday Cup detector.
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Production Plant
IMA Life North America
QUANTUM Highlights
1.
The Graphical User Interface (GUI) offers advanced features to support routine operation, while empowering skilled users to add customised capabilities
2.
Easy integration with new or existing freeze dryers, both pilot and production-scale.
3.
QUANTUM samples freeze dryer chamber air to detect vaporized silicone oil.
4.
When helium is introduced at the leak source, QUANTUM enables detection of the leak.
5.
Primary and secondary drying monitor the cycle and ensure its efficient completion.
QUANTUM system is ready for Ethernet port communications and easy-to-use software and user interface.
- Technical Data
- Machine Layout
| TECHNICAL DATA QUANTUM | |
| Measurement specification |
Conditions/units |
| Installation | Complete in 2 working days |
| Mass range | 1-200 amu |
| Resolution | Better than 10% valley between peaks of equal height throughout the mass range |
| Communication interfaces | Ethernet |
| Mass number stability | Better than +/- 0.1amu over 8hrs |
|
Minimum detectable partial pressure |
<2e-11 Torr |
|
Minimum detectable concentration |
<100ppb for all common gases except <10ppm for H2 (trace gas detection limit) |
|
Maximum operational pressure |
500 mTorr |
|
Electron energy |
25 V – 100 V (70 V default setting) |
|
Weight |
20 kg |
|
Ambient temperature |
10°C to 40°C |
| Power consumption | 88-264 VAC, 47/63 Hz, 600 Watts |
| Pneumatics |
60-80 psig CDA |