Although one of the oldest techniques in the pharmaceutical industry for the preservation of unstable materials, there has been an increasing demand for lyophilized products and equipment, in particular in the last decade. In fact today, about half of all sterile injectables are lyophilized.
The freeze-drying process of today demands increased process control, with reduced processing time augmented with upgrades in equipment to remain compliant with a changing regulatory landscape. To accommodate such growth, IMA LIFE uses its in-depth process knowledge to make freeze drying faster, safer, cheaper, and compatible with all industry requirements and challenges.
LYOMAX configurable options and custom designs provide the optimal solution for each application.
LYOMAX meets the highest possible technical requirements, the strictest standards of the global licensing authorities, and comply with all the current guidelines such as GAMP, cGMP, FDA etc.
IMA Lyomax freeze dryers embody the requirements of the pharmaceutical industry for faster, safer, cheaper and more ecologically friendly processes:
• The IMA Life patented FusionTM shelves reduce energy consumption typically in heating, cooling and steam sterilization thus achieving a reduction in energy costs and fast temperature response. The FusionTM shelves allow for a 20% reduction in weight leading to reduced energy consumption during freeze drying and sterilization.
• PAT tools reduce overall process time and energy consumption.
• IMA Life is developing innovative eco-friendly refrigeration for freeze dryers, the KryoAir. The KryoAir is a new 100% green refrigeration technology using the ultimate natural refrigerant “air”. The system is based on a series of compression/cooling/ expansion steps of air, which can be cooled to a temperature as low as -100° C.
Configurations including integral condenser, external condenser, two-story and pass through designs.
Two stage reciprocating semi-hermetic/screw compressors/liquid nitrogen refrigeration system.
Shelf cooling to -55/70°C and condenser cooling to -75/120°C. HFC/LN2 refrigerants.
Integrated automatic, semi-automatic and manual loading/unloading systems.
Vacuum measurements with capacitance manometers.
VERISEQ® advanced technology using sterile liquid nitrogen to control the nucleation process during pharmaceutical freeze drying.
The Lyomax series offers the most comprehensive range of custom-built freeze-dryers for those who require more than a standard solution. Lyomax can provide the answer from 1 m2 to 100 m2 applying state-of-the-art engineering in vacuum, refrigeration, stoppering and heat-transfer technology.