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BARRIER TECHNOLOGY: OPEN & CLOSED RABS
Barrier Technologies for Aseptic Fill-finish Lines

Open RABS represent the first solution available in the barrier technology scenario, introducing the concept of product protection.
Closed RABS provide minimal protection during manipulation of mildly potent products.

Open RABS represent the first solution available in the barrier technology scenario, introducing the concept of product protection.
Closed RABS provide minimal protection during manipulation of mildly potent products.

Safety first, for both product and operator.

 

Open RABS is a simple solution, used extensively in the pharmaceutical sector, to separate the production area from the operator and the external environment. Product protection is only effective if the airflow is active, whereas no protection is offered to the operator when potent compounds are being processed. Easy to install and a cost-effective solution, it is the minimum barrier solution to be used in case of aseptic production environments.

Closed RABS is an evolution of the “Open” solution, providing a minimal degree of operator protection when potent compounds are being processed.

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Sustainability

IMA has always been committed to reducing the environmental impact of its equipment, addressing the issue of consumption through design choices, high-efficiency components and optimizing the control dynamics on processing machines such as barrier technologies (Open RABS and Closed RABS).

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BARRIER TECHNOLOGY: OPEN & CLOSED RABS Highlights

1.
Unidirectional Air Flow (UAF)
2.
Easy to validate (air flow, air classification, doors interlocks)
3.
Production area access control (doors can be interlocked)
4.
Automatic or semiautomatic WIP cycles (cRABS, only)
5.
Ergonomic applications
6.
Class B surrounding protection area
7.
No-leak tightness
8.
Cost-saving with respect to isolation technology solutions
The oRABS and some versions of the cRABS, are easily installed on top of any standard filling line for aseptic products. In most cases, they can be installed in existing lines and are widely accepted for aseptic production, as well.
  • Machine Layout
BARRIER TECHNOLOGY: OPEN & CLOSED RABS Layout

BARRIER TECHNOLOGY: OPEN & CLOSED RABS Gallery

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oRABS - Connection to the segregated capping area
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cRABS-Alu capping area
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oRABS-Vial feeding
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oRABS-Vial transfer
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Example of complete line with oRABS for liquid and lyo products – front view
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Example of complete line with oRABS for liquid and lyo products – side view
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