Barrier Technology • Pharma • IMA Group

Open RABS, Closed RABS and Isolators. Isotech Lab, Isolation Technology and Engineered HVAC. Get an insight of the latest IMA technological breakthrough.

Open RABS, Closed RABS and Isolators: Focus on Energy Savings

RABS means Reduced Access Barrier System, it is a rigid protection made of transparent walls (polycarbonate or glass), equipped with an adequate number of glove flanges and gloves. It is installed on top of the filling and/or capping machines, separating them from the surrounding area.
Gloves must be positioned in order to allow the operator to perform all operations inside the machine, such as cleaning, caps/stoppers loading, vials removal, etc. so that these can be performed by operators without opening the protection walls.

IsoTech Lab • In-House Isolator Research & Development Laboratory

IMA Life In-house Isolator Research & Development Laboratory is a pharmaceutically compliant lab hosting an infeed Rotary Table and a Filling & Stoppering machine under isolator to specifically carry out tests and ultimately demo runs. A microbiologist staff works aside our engineers to improve the isolator HVAC systems as well as to determine even shorter and well suited H2O2 cycle times for our equipment. Cooperation agreements have been settled with scientists and experts on the field to support the pragmatic and industrial approach.

IMA Life Research & Development Lab for Isolators has two main objectives:

1) To perform internal researches:

To optimize VHP cycles;
To check the performance of electro mechanical components of the HVAC circuits;
To make comparisons between VHP generators and other sanitization media;
To check material compatibility and resistance to decontamination agents.

2) To set-up activities in conjunction with Customers:

To check cycle times with agreed isolator loadings;
To perform preliminary training sessions for Customer isolator management and VHP development cycles.

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Isolation Technology and Engineered HVAC

A filling line for aseptic products in isolation technology offers a wide number of advantages with respect to a similar line installed in a conventional clean-room or with an open RABS.

We can summarize these benefits in the following topics:

increased product safety (that results in an increased product quality)
higher operator protection (in case of toxic product)
production area in class C or D, instead of class A or B
possibility to frequently perform cleaning and sterilization cycles