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book Papers

We share our expertise and our constant commitment towards innovation. A selection of scientific papers, often presented during the main international conferences, to share our research and contribute to the body of pharmaceutical science.

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How to step-up metformin tablets production from a pilot scale coater to three different industrial scale equipment.

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How to enhance tableting production with a paracetamol based formulation.

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Metformin manufacturing: scale-up from middle-size to large-size rotary tablet press.

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Perfect adaptability for truly continuous production.

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Preliminary results of predictive maintenance algorithms on a tablet press production machine.

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Prexima and Croma, integrated technologies for Continuous Manufacturing.

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Matrix minitablets produced by direct compression on Prexima 80: influence of operative and formulative parameters

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LYNFINITY: continuous aseptic spray freeze drying. Process, Technology and Product Characterization.

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Selecting the proper formulation and production parameters for the development of orodispersible tablets on a Prexima 80

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Informed Manufacturing through Big Data Analytics of Freeze Drying Process and Equipment.

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A molecular perspective in Freeze Drying with the Quantum Mass Spectrometer.

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LYnfinity is just the drop away

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LYnfinity – Drying Technology

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Today, freeze dryer can use a 100% green refrigeration system, using air as the refrigeration fluid.

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DSMC simulations of vapor flow and ice dynamics in a freeze dryer condenser.

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Freeze-Drying Process Optimization.

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Increasing Vial to Vial Homogeneity: An Analysis of VERISEQ® Nucleation on Production Scale Freeze Dryers.

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Lynfinity – Freezing

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How to perform a good scale-up

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LYnfinity – Spraying

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Achieving and maintaining GAMP® 5 compliance: IMA Active’s risk-based approach to software development and verification

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Application of a fractional factorial design for the evaluation of a coating process

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Coating optimization: equipment features to prevent defects

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Development of an automated multi-stage continuous reactive crystallization system with inline PATs for high viscosity process

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Drug layering: the impact of up-scaling

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How to monitor HPMC concentration through conductivity measurement

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Prexima 300. Determination of the effect of the pre-compression force on the tablet hardness, obtained at constant value of the main compression force

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Scaling up a film coating process

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Suggestions for choosing an appropriate tablet press feeding system

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Impact of Container Closure System on Freeze Drying Process.

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Validation of the Cleaning in Place of the coating pan PERFIMA, IMA

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