What is CROMA in your view?

What if while working with tablets their weight and hardness fluctuate? What is the best way to handle challenging powders when standard solutions don’t work? Discover how to work on the feeder system and how to adjust the upper punch penetration to obtains a stronger tablet and lower relative standard deviation.

What if adding lubricant is not allowed or does not solve the problem? What is the best way to resolve sticking or picking when standard solutions don’t work? Discover how to avoid powder particles to adhere to the metal surfaces and obtain extremely satisfying results.

What if working in the upper part of dies is not the solution? What is the best way to perform capping or lamination when standard solutions don’t work?

Developing a revolutionary freeze-drying technology always requires some form of lateral thinking. One challenge was to find a way of making the freeze-dried product compatible with a variety of containers. Typically, freeze-dried products were handled in vials or on bulk trays limiting the use of alternate emerging containers. The intuition our LAB4Life team had in Tonawanda at the IMA Life North America facilities turned the issue on its head and adapted the product form to any container.
Watch the video and see how a game of golf changed the approach and contributed to the success of LYnfinity’s spray freeze-drying technology.

Especially since the planet is faced with a pandemic, freeze drying has come under a lot of attention. Efficiency, simple supply chains, a need for large volumes are factors that have driven the development of technologies such as those of our LYnfinity spray freeze-drying solution. One issue we need to re-think was the heat and mass transfer. Many technological innovations are born thanks to a strange intuition, a sort of Eureka moment and this is what happened when we realised it would work by freezing the drug as a pellet and drying it without a container, improving heat and mass transfer, ultimately resulting in reduced drying time.
Discover how we came upon the idea for the spray freeze drying procedure in this video.

Developing a revolutionary freeze-drying technology always requires some form of lateral thinking. One challenge was to find a way of making the freeze-dried product compatible with a variety of containers. Typically, freeze-dried products were handled in vials or on bulk trays limiting the use of alternate emerging containers. The intuition our LAB4Life team had in Tonawanda at the IMA Life North America facilities turned the issue on its head and adapted the product form to any container.
Watch the video and see how a game of golf changed the approach and contributed to the success of LYnfinity’s spray freeze-drying technology.